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A randomized blind placebo-controlled trial investigating the effects of photobiomodulation therapy (PBMT) on canine elbow osteoarthritis

A randomized double-blind placebo-controlled trial of forty participants with knee osteoarthritis, aged between 50 and 75 years.

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Low-level laser therapy acts differently on mRNA expression of anti- and pro-inflammatory mediators in collagenase-induced tendinitis in rat

A rat model of induced tendonitis was used to evaluate the effect of laser therapy on inflammatory signaling. The laser…

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Characterization of macrophage/microglial activation and effect of photobiomodulation in the spared nerve injury model of neuropathic pain

A Spared Nerve Injury model was performed on rats and mechanical allodynia was assessed with an electronic Von Frey device.

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The mechanistic basis for photobiomodulation therapy of neuropathic pain by near infrared laser light

This study investigated the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain.

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The comparison of effects between pulsed and CW lasers on wound healing

This study evaluated both CW and pulsed laser therapy in an elliptic wound model in rats.  This study is one…

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Comparison of light penetration of continuous wave 810 nm and superpulsed 904 nm wavelength light in anesthetized rats

This study examines the 2012 publication by Joensen et al. Transmission through an anesthetized rat skin flap with a continuous…

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Effect of near-infrared light exposure on mitochondrial signaling in C2C12 muscle cells.

Our data indicates that NIR light alters mitochondrial biogenesis signaling and may represent a mechanistic link to the clinical benefits.

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Phototherapy promotes regeneration and functional recovery of injured peripheral nerve

This review presents several studies that evaluate the efficacy of laser therapy to promote regeneration and recovery of injured peripheral…

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Low-level laser therapy in acute pain: A systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials

Review the biological and clinical short-term effects of low-level laser therapy (LLLT) in acute pain from soft-tissue injury.

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Mechanisms of low level light therapy

This review paper covers the current theory on basic mechanisms of laser therapy.

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